Why do so many patients with Ehlers-Danlos Syndromes (EDS) and Hypermobility Spectrum Disorders (HSD) have symptoms that seem… everywhere?
Skin. Gut. Heart. Brain.
It may not be separate problems.
It may be mast cells.
On today’s episode of @bendy_bodies, I shared how my understanding of mast cell activation has changed, and why it may play a much bigger role in EDS and HSD than we once thought.
I used to think mast cell activation syndrome (MCAS) affected a small subset of patients.
In practice, that has not been my experience.
Mast cells are present in nearly every tissue in the body.
When they release inflammatory mediators, they can affect multiple systems at once, including the skin, gastrointestinal tract, cardiovascular system, and nervous system.
That helps explain why symptoms can feel so widespread and so difficult to connect.
And why many patients are told their symptoms are unrelated.
When we support mast cell stability, we often see improvements across systems, not just in one isolated area.
Pain may improve.
GI symptoms may calm down.
Heart rate and lightheadedness may become more manageable.
Because mast cells interact with nerves, blood vessels, and connective tissue, treating them can sometimes shift the entire system.
Not just one symptom.
Conversations like this matter because these conditions are not isolated.
They are interconnected.
And when we treat them that way, outcomes can change.
💬 Have you noticed improvement when addressing mast cell activation?
#BendyBodies #MastCellActivation #MCAS #EhlersDanlos #Dysautonomia
📌 Medical Advice Disclaimer: This content is for educational purposes only and is not medical advice. Always consult your healthcare provider for personalized care.
VD: Video clip featuring Dr. Linda Bluestein wearing headphones and speaking into a microphone discussing mast cell activation, EDS, HSD, and systemic inflammation.
