Dr. Afrin trained and practiced as an internist and hematologist/oncologist at the Medical University of South Carolina 1984-2014 and further practiced at the University of Minnesota 2014-2017, coming to focus his interests in mast cell disease since the mid-’00s. Since 2017, he has been practicing in New York and has been helping to develop a global network of clinicians and investigators for advancing care, research, and education in this area. He has published highly accessed articles about mast cell activation syndrome and a popular book in the field.